Publications

Journal Article

Xianyuan Xiang, Karin Wind, Thomas Wiedemann, Tanja Blume, Yuan Shi, Nils Briel, Leonie Beyer, Gloria Biechele, Florian Eckenweber, Artem Zatcepin, Sven Lammich, Sara Ribicic, Sabina Tahirovic, Michael Willem, Maximilian Deussing, Carla Palleis, Boris-Stephan Rauchmann, Franz-Josef Gildehaus, Simon Lindner, Nicolai Franzmeier, Karlheinz Baumann, Axel Rominger, Peter Bartenstein, Sibylle Ziegler, Alexander Drzezga, Gesine Respondek, Katharina Buerger, Robert Perneczky, Johannes Levin, Günter U Höglinger, Jochen Herms, Christian Haass, Matthias Brendel (2021)
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases
Sci Transl Med. 2021 Oct 13;13(615):eabe5640.
Kai Schlepckow, Kathryn M. Monroe, Gernot Kleinberger, Ludovico Cantuti-Castelvetri, Samira Parhizkar, Dan Xia, Michael Willem, Georg Werner, Nadine Pettkus, Bettina Brunner, Alice Sülzen, Brigitte Nuscher, Heike Hampel, Xianyuan Xiang, Regina Feederle, Sabina Tahirovic, Joshua I. Park, Rachel Prorok, Cathal Mahon, Chun-Chi Liang, Ju Shi, Do Jin Kim, Hanna Sabelström, Fen Huang, Gilbert Di Paolo, Mikael Simons, Joseph W. Lewcock, Christian Haass (2020)
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region
EMBO Mol Med. 2020 Apr 7;12(4):e11227.
Vöglein J, Willem M, Trambauer J, Schönecker S, Dieterich M, Biskup S, Giudici C, Utz K, Oberstein T, Brendel M, Rominger A, Danek A, Steiner H, Haass C, Levin J (2019)
Identification of a rare presenilin 1 single amino acid deletion mutation (F175del) with unusual amyloid-β processing effects
Neurobiol Aging. 2019 Dec;84:241.e5-241.e11
Samira Parhizkar, Thomas Arzberger, Matthias Brendel, Gernot Kleinberger, Maximilian Deussing, Carola Focke, Brigitte Nuscher, Monica Xiong, Alireza Ghasemigharagoz, Natalie Katzmarski, Susanne Krasemann, Stefan F. Lichtenthaler, Stephan A. Müller, Alessio Colombo, Laura Sebastian Monasor, Sabina Tahirovic, Jochen Herms, Michael Willem, Nadine Pettkus, Oleg Butovsky, Peter Bartenstein, Dieter Edbauer, Axel Rominger, Ali Ertürk, Stefan A. Grathwohl, Jonas J. Neher, David M. Holtzman, Melanie Meyer-Luehmann, Christian Haass (2019)
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
Nat Neurosci. 2019 Feb;22(2):191-204
Matthias Brendel, Anna Jaworska, Felix Overhoff, Tanja Blume, Federico Probst, Franz-Josef Gildehaus, Peter Bartenstein, Christian Haass, Bernd Bohrmann, Jochen Herms, Michael Willem, Axel Rominger (2018)
Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional Aβ deposition rate and plaque burden at treatment initiation
Theranostics. 2018 Sep 9;8(18):4957-4968
Anna Daria, Alessio Colombo, Gemma llovera, Heike Hampel, Michael Willem, Arthur Liesz, Christian Haass, Sabina Tahirovic (2016)
Young microglia restore amyloid plaque clearance of aged microglia
EMBO J. 2016 Dec 21. pii: e201694591. doi: 10.15252/embj.201694591. [Epub ahead of print]