Ludwig-Maximilians-Universität, Chair of Metabolic Biochemistry
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B5 aktuell - Gesundheitsmagazin

Blick ins Labor: Schwimmende Alzheimer-Modelle

[Only in German language]Rund eine Million Menschen leiden in Deutschland an der Alzheimerschen Krankheit. Weltweit sind es Schätzungen zufolge zwischen 12 und 18 Millionen Menschen. Tendenz steigend, vor allem, weil die Menschen immer älter werden und Alzheimer eine Krankheit ist, die meistens im fortgeschrittenen Alter auftritt. Heilen kann man Alzheimer noch nicht, auch wenn unter Hochdruck an Medikamenten gearbeitet wird. Auch an der Ludwig-Maximilians-Universität München werden Wirkstoffe gegen das Sterben im Kopf erforscht, und zwar mithilfe von Zebrafischen.

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LMU Tonspur Forschung

Das grosse Vergessen

[Only in German language]In dem Audiocast „Tonspur Forschung“ ist die bekannte Podcasterin Annik Rubens an der LMU spannenden Forschungsfragen auf der Spur. Die Ergebnisse ihrer „Erkundungen“ werden einmal pro Monat als Podcast auf dem Online-Bildungsportal LMU on iTunes U präsentiert.

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DFG ScienceTV - Search for a cure

It is more than a hundred years since Alois Alzheimer first described the disease that is named after him. Alzheimer's disease is an illness in which nerve cells in the brain slowly die off. People affected by Alzheimer's suffer from impaired memory and orientation, and their capacity for thinking and judgment is restricted. These impairments make it increasingly difficult to cope with normal everyday life. The patients are increasingly reliant on help and support. Alzheimer’s disease can occur in people below the age of 50, but it is usually older persons who are affected. In the brain of Alzheimer’s patients, characteristic protein deposits (amyloid plaques) can be detected under the microscope, but in spite of intensive research there are still no drugs that can stop this illness.

Prof. Dr. C. Haass of the German Centre for Neurodegenerative Diseases at the Ludwig Maximilian University in Munich has been investigating the molecular causes of Alzheimer’s disease for some years now. In order to test new approaches to treatment however, animal models are required that can be used to track the illness and the therapeutic capabilities of drug treatments. As a suitable animal model, Prof. Haass has chosen the zebra fish.

YouTube Channel DFGScienceTV - Search for a cure