Ludwig-Maximilians-Universität, Chair of Metabolic Biochemistry
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As stated by the prevailing amyloid cascade hypothesis, Alzheimer’s disease (AD) is caused by the aggregation and cerebral deposition of long amyloid-beta peptide (Abeta) species, which are released from a C-terminal amyloid precursor protein fragment by gamma-secretase. more

A multicenter study led by LMU‘s Christian Haass and Michael Ewers has identified a biomarker associated with the activation of an innate immune response to neural damage during early stages of Alzheimer’s disease. more