Dominik Paquet awarded
Winner of the Verum Award 2009 and the Leda Hanin Award for AD/PD
16.03.2009
Verum Award 2009
At the opening ceremony of the AD/PD 9th International Conference in Prague, Czech Republic, the Congress President Dr. Avraham Fisher presented the VERUM Award 2009 to four young scientists from Belgium and Germany. They received the award in recognition of their outstanding scientific achievements within the EU-funded research project MEMOSAD. Kerensa Broersen and Inna Kuperstein from the Vlaams Instituut voor Biotechnologie (VIB) together were honoured with a 1st prize of 3000.00 Euro, Dominik Paquet from the Ludwig-Maximilians-Universität München was honoured with a 2nd prize of 2.000.00 Euro, while Lutgarde Serneels, also from the Vlaams Instituut voor Biotechnologie, was granted a 3rd prize with 1000.00 Euro. ...
Dominik Paquet, a PhD student in the Laboratory for Neurodegenerative Disease Research at the Adolf Butenandt Institute in Munich, was awarded the 2nd prize for his presentation “A novel tau transgenic zebrafish model for drug discovery”. The research group developed a novel tau transgenic zebrafish model and investigated with this system the efficacy of two inhibitors of tau phosphorylation identified in a high-throughput screening process. While both inhibitors were highly active in cell cultures, only one of them displayed in vivo activity which is the prerequisite for its utilization as a therapeutic drug in Alzheimer disease. The new zebrafish transgenesis technology allows the modelling of numerous other human disorders which are based on misfolding or overexpression. ...
